Hugo van der Goes was probably born in Ghent, where he was active from 1467. He was the most important Ghent painter of the period after
Jan van Eyck. His 'Portinari Altarpiece' arrived in Florence in 1483 where it made a considerable impression and influenced a number of artists, including
Ghirlandaio.
About 1475 or rather later, van der Goes entered the monastery of the Rode Klooster, Brussels, where he continued to paint, although suffering bouts of melancholia and delirium.